Learn how an emerging NAM is helping advance more efficient, human-relevant strategies for assessing thyroid hormone disruption while reducing reliance on animal testing. 

Endocrine-disrupting chemicals are widespread, yet traditional approaches to thyroid toxicity testing often rely on resource-intensive animal studies or models that lack human relevance. New approach methods are helping address these limitations.

In this webinar, guest speaker Chad Deisenroth, PhD, Principal Laboratory Toxicologist, Center for Chemical Informatics and Screening at ULRI Chemical Insights, will share insights from a collaborative validation effort of a novel human 3D thyroid microtissue assay to directly assess thyroid hormone synthesis.

Key Topics:

• Global Health Risk: Endocrine-disrupting chemicals are widespread and threaten human health by interfering with hormonal systems.
• Screening Bottleneck: Current hazard identification relies on resource-intensive animal testing, which is too slow and costly to address the vast chemical landscape. 
• Innovative Solution: Human thyroid microtissues provide a faster, biologically relevant alternative for thyroid toxicity screening.

Guest Speaker: 

Chad Deisenroth, PhD, Principal Laboratory Toxicologist, Center for Chemical Informatics and Screening at UL Research Institutes' Chemical Insights

Dr. Chad Deisenroth earned his Ph.D. in Genetics and Molecular Biology from the University of North Carolina at Chapel Hill and completed postdoctoral training in chemical safety sciences at The Hamner Institutes for Health Sciences.

Prior to joining UL Research Institutes, Dr. Deisenroth served as a principal investigator in the Center for Computational Toxicology and Exposure at the U.S. Environmental Protection Agency, where he advanced the development and application of in vitro new approach methods - or NAMs - for predictive toxicology. His work at the EPA centered on engineering human-relevant cell culture models and innovative testing approaches to improve the speed, reliability, and biological relevance of chemical hazard identification for human health effects.

Dr. Deisenroth has authored numerous peer‑reviewed publications in leading toxicology journals and received recognition for several high‑impact contributions in the field of in vitro toxicology. He has also led U.S. efforts to validate NAM technology in collaboration with international partners and currently contributes to an OECD working group focused on standardizing and implementing NAMs for endocrine toxicity testing.

View On-Demand Webinar: Improving Confidence in Thyroid Hormone Disruption Assessment Using a Novel Human-Relevant In Vitro Model